Numerical simulation of coronary arteries blood flow: effects of the aortic valve and boundary conditions

Abstract. Sudden cardiac death in athletes is often related to anomalies coronary origin, which may affect how arteries supply blood the heart; this highlights importance of understanding perfusion. Studies for simulation and predictions flow under normal or disease conditions are many. Numerical simulations can provide rich information about with reduced costs relation physical models. Correct numerical still challenging due complex interactions upstream, e.g., aortic root, downstream, ventricular contraction, parts arteries. Among all, intrinsic ability artery autoregulation, intramyocardial resistance, frequency, valve functioning could significantly In present study, we aim at investigating effects boundary on We numerically modeled, by means ANSYS-Fluent software, inside proximal left right arteries, sinuses Valsalva, ascending aorta without valve; geometry computational model represents average healthy person. Physiological values have been applied domain boundaries achieve a stable solution Navier-Stokes equations, govern incompressible, laminar, Newtonian flow. Our results give insight into proper setup predict